6H05

CAS No. 1469338-01-9

6H05( K-Ras inhibitor )

Catalog No. M12006 CAS No. 1469338-01-9

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 116 In Stock
10MG 203 In Stock
25MG 337 In Stock
50MG 500 In Stock
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Biological Information

  • Product Name
    6H05
  • Note
    Research use only, not for human use.
  • Brief Description
    6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).
  • Description
    6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    K-Ras inhibitor
  • Pathway
    MAPK/ERK Signaling
  • Target
    Ras
  • Recptor
    K-Ras(G12C)
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1469338-01-9
  • Formula Weight
    476.1191
  • Molecular Formula
    C20H30ClN3O2S3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    OC(=O)C(F)(F)F.CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC1=CC=C(Cl)C=C1
  • Chemical Name
    4-Piperidinecarboxamide, 1-[2-[(4-chlorophenyl)thio]acetyl]-N-[2-[[2-(dimethylamino)ethyl]dithio]ethyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ostrem JM, et al. Nature. 2013 Nov 28;503(7477):548-51.
molnova catalog
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